Gene Detail


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Gene Symbol TUSC3
Synonyms D8S1992 | M33 | MagT2 | MRT22 | MRT7 | N33 | OST3A | SLC58A2
Gene Description TUSC3, tumor suppressor candidate 3, regulates protein glycosylation (PMID: 24685145) and plays a role in magnesium transport and homeostasis (PMID: 19717468, PMID: 28272772). Decreased expression of Tusc3 has been observed in pancreatic (PMID: 26871953) and renal cell carcinoma (PMID: 31186719), increased promoter methylation has been identified in ovarian cancer (PMID: 23096450) and glioblastoma (PMID: 27177902), and overexpression of Tusc3 has been observed in colorectal cancer (PMID: 30115537) and non-small cell lung cancer (PMID: 28487226).
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