Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||SIAA0862 | SOC2 | SUR8|
|Gene Description||SHOC2, leucine-rich repeat protein SHOC-2, is a scaffold protein that forms a complex with protein phosphatase 1 (PP1c) to activate Raf1 kinase and subsequent ERK1/2 signaling (PMID: 27574535, PMID: 26876614). Preclinical studies have implicated Shoc2 in tumorgenesis through accelerated activation of ERK1/2 kinase (PMID: 27574535).|