Gene Detail

Gene Symbol COL18A1
Synonyms KNO | KNO1 | KS
Gene Description COL18A1, collagen alpha-1(XVIII) chain, may play a major role in determining retinal structure and neural tube closure. COL18A1 encodes the endostatin chain which can inhibit endothelial cell proliferation and angiogenesis and endostatin is implicated in the prognosis of human cancer (PMID: 20361288; PMID: 21815140).
Entrez Id 80781
Chromosome 21
Map Location 21q22.3
Canonical Transcript NM_130444

Additional content available in CKB BOOST