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| Gene Symbol | CALR | ||||||||||
| Synonyms | CALR1 | cC1qR | CRT | HEL-S-99n | RO | SSA | ||||||||||
| Gene Description | CALR, calreticulin, is a Ca2+ binding chaperone protein that plays a role in multiple biological processes, including protein folding and quality control, calcium homeostasis, immune response, cell adhesion and migration, and cell signaling (PMID: 19940256, PMID: 28470469, PMID: 22959412). CALR frameshift mutations have been identified in myeloproliferative neoplasms, including essential thrombocytothemia and myelofibrosis (PMID: 24365789, PMID: 28470469). | ||||||||||
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