Gene Detail


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Gene Symbol SMC1A
Synonyms CDLS2 | DEE85 | DXS423E | EIEE85 | SB1.8 | SMC1 | SMC1alpha | SMC1L1 | SMCB
Gene Description SMC1A, structural maintenance of chromosomes 1A, is a member of the cohesion complex, which potentially regulates cell cycle, and plays a role in the cellular proliferation, migration and apoptosis (PMID: 23426528, PMID: 29988990; PMID: 30242889). Mutations in SMC1A have been identified in colorectal cancer, and overexpression has been demonstrated in colorectal carcinoma (PMID: 30823889), hepatocellular carcinoma (PMID: 29988990), and prostate cancer (PMID: 30242889).
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