Gene Detail

Gene Symbol BAP1
Synonyms HUCEP-13 | hucep-6 | UCHL2
Gene Description BAP1, BRCA1 associated protein 1, belongs to the ubiquitin C-terminal hydrolase subfamily and interacts with the RING finger domain of the BRCA1 protein, resulting in deubiquitylation of BARD1 (PMID: 23550303). BAP1 germline mutations are associated with mesothelioma and melanoma (PMID: 23550303) and somatic mutations are highest in renal and endometrial cancers (PMID: 27283171).
Entrez Id 8314
Chromosome 3
Map Location 3p21.1
Canonical Transcript NM_004656

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