Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Synonyms||HUCEP-13 | hucep-6 | KURIS | TPDS1 | UBM2 | UCHL2 | UVM2|
|Gene Description||BAP1, BRCA1 associated protein 1, belongs to the ubiquitin C-terminal hydrolase subfamily and interacts with the RING finger domain of the BRCA1 protein, resulting in deubiquitylation of BARD1 (PMID: 23550303) and is associated with genomic stability (PMID: 31747945). BAP1 germline mutations are associated with mesothelioma and melanoma (PMID: 23550303) and somatic mutations are highest in renal and endometrial cancers (PMID: 27283171).|