Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol BRIP1
Synonyms BACH1 | FANCJ | OF
Gene Description BRIP1, BRCA1 interacting protein C-terminal helicase 1, is involved in DNA repair and aids the tumor suppressor function of Brca1 (PMID: 14983014). BRIP1 germline mutations are associated with breast and ovarian cancers and somatic mutations are highest in endometrial, colon, and NSCLC (PMID: 27283171).


Additional content available in CKB BOOST