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Gene Symbol USP42
Gene Description USP42, ubiquitin specific peptidase 42, mediates deubiquitylation of target proteins, which leads to protein stabilization (PMID: 25336640). A RUNX1-USP42 fusion has been identified in acute myeloid leukemia (PMID: 24673627) and an USP42-EGFR fusion has been identified in lung adenocarcinoma (PMID: 31064887).
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