Gene Detail

Gene Symbol TRAF7
Synonyms CAFDADD | RFWD1 | RNF119
Gene Description TRAF7, TNF receptor-associated factor 7, E3 ubiquitin protein ligase, acts as an E3 ligase for multiple NF-kappaB pathway members and for p53, and plays a role in regulation of several signaling pathways and in promoting apoptosis (PMID: 23128672, PMID: 22105767). Mutations in TRAF7 are associated with non-NF2 meningiomas (PMID: 23348505).
Entrez Id 84231
Chromosome 16
Map Location 16p13.3
Canonical Transcript NM_032271

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