Gene Detail


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Gene Symbol AKR1C3
Synonyms DD3 | DDX | HA1753 | HAKRB | HAKRe | hluPGFS | HSD17B5 | PGFS
Gene Description AKR1C3, aldo-keto reductase family 1 member C3, is an enzyme that catalyzes the conversion of 17-ketoreduction thus contributing to androgen biosynthesis (PMID: 23748150). Overexpression of Akr1c3 has been implicated in castration-resistant prostate cancer, breast cancer, and acute myeloid leukemia (PMID: 30012349).
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