Gene Detail

Gene Symbol CCNE1
Synonyms CCNE | pCCNE1
Gene Description CCNE1, G1/S-specific cyclin-E1, predominately interacts with CKD2 to regulate the cell-cycle in transition from G1 to S phase (PMID: 14965268, PMID: 27461360). Amplification and/or overexpression of CCNE1 is common in chemoresistant ovarian high grade serous carcinomas (PMID: 27461360), and in general, is associated with poor prognosis in solid tumor types (PMID: 30026836).
Entrez Id 898
Chromosome 19
Map Location 19q12
Canonical Transcript NM_001238

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