Gene Detail
Contact
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
| Gene Symbol | MAP3K14 | ||||||||||
| Synonyms | FTDCR1B | HS | HSNIK | IMD112 | NIK | ||||||||||
| Gene Description | MAP3K14, mitogen-activated protein kinase kinase kinase 14, encodes for a serine/threonine protein kinase that activates the NF-kappaB pathway and plays a large role in immune regulation (PMID: 20685151, PMID: 22718757, PMID: 32033109). MAP3K14 amplification has been identified in Hodgkin lymphoma, multiple myeloma, and splenic marginal zone lymphoma (PMID: 22469134). | ||||||||||
|
|||||||||||
Additional content available in 
CKB BOOST
CKB BOOST
