Gene Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at :

Gene Symbol MAP3K14
Synonyms FTDCR1B | HS | HSNIK | IMD112 | NIK
Gene Description MAP3K14, mitogen-activated protein kinase kinase kinase 14, encodes for a serine/threonine protein kinase that activates the NF-kappaB pathway and plays a large role in immune regulation (PMID: 20685151, PMID: 22718757, PMID: 32033109). MAP3K14 amplification has been identified in Hodgkin lymphoma, multiple myeloma, and splenic marginal zone lymphoma (PMID: 22469134).
Additional content available in CKB BOOST