Gene Detail


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Gene Symbol KNSTRN
Synonyms C15orf23 | HSD11 | ROCHIS | SKAP | TRAF4AF1
Gene Description KNSTRN, kinastrin, is a kinetochore-associated protein that regulates the cell cycle (PMID: 19667759) and chromosomal stability (PMID: 25194279), and plays a role in cellular apoptosis (PMID: 24718257). KNSTRN is broadly expressed in various tissues and mutations have been observed in cutaneous squamous cell carcinoma (PMID: 25194279) and basal cell carcinoma (PMID: 26348826).
Additional content available in CKB BOOST