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Gene Symbol CD4
Synonyms CD4mut
Gene Description CD4, CD4 molecule, is a glycoprotein that recognizes MHC class II peptides on antigen-presenting cells, regulates activation of T-lymphocytes leading to proliferation and differentiation of effector T-cells, and plays a key role in adaptive immune response (PMID: 22474485, PMID: 8057386). CD4 expression is associated with poor survival in acute myeloid leukemia patients (PMID: 9436919).


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