Gene Detail

Gene Symbol AURKB
Synonyms AIK2 | AIM-1 | AIM1 | ARK-2 | ARK2 | AurB | aurkb-sv1 | aurkb-sv2 | IPL1 | PPP1R48 | STK-1 | STK12 | STK5
Gene Description AURKB, aurora B kinase, is a serine-threonine protein kinase, which plays a role in the separation of daughter chromatids during cell division and functions in regulation of genomic stability (PMID: 28095398). Overexpression of Aurkb has been associated with poor prognosis in solid tumors, such as non-small cell lung cancer (PMID: 28095398), and in leukemia (PMID: 22940834, PMID: 26199132).
Entrez Id 9212
Chromosome 17
Map Location 17p13.1
Canonical Transcript NM_004217

Additional content available in CKB BOOST