Gene Detail
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| Gene Symbol | RPS6KA5 | ||||||||||
| Synonyms | MSK1 | MSPK1 | RLPK | ||||||||||
| Gene Description | RPS6KA5, ribosomal protein S6 kinase A5, is a mitogen and stress activated kinase (MSK) that phosphorylates a number of transcription factors including, CREB1 and ATF1, to promote cell proliferation and may regulate the immune system (PMID: 29327245). Overexpression of Rps6ka5 has been observed with increased survival in breast cancer patients (PMID: 29327245) and poor prognosis in colorectal cancer (PMID: 28314603) and glioma (PMID: 30020192). | ||||||||||
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