Gene Detail

Gene Symbol AIM2
Synonyms PYHIN4
Gene Description AIM2, interferon-inducible protein AIM2, regulates assembly of the inflammasome, induces apoptosis, and prevents proliferation of tumor cells (PMID: 21804607, PMID: 28243117). Loss of Aim2 expression has been shown in liver cancer (PMID: 27167192), to result in Akt activation in colorectal cancer (PMID: 26107252, PMID: 28243117), and may be prognostic for poor outcomes in renal cell carcinoma (PMID: 30031129).
Entrez Id 9447
Chromosome 1
Map Location 1q23.1-q23.2
Canonical Transcript NM_004833

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