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Gene Symbol ENTPD1
Synonyms ATPDase | CD39 | NTPDase-1 | SPG64
Gene Description ENTPD1 (CD39), ectonucleoside triphosphate diphosphohydrolase 1, converts ATP to adenosine to regulate cellular homeostasis and functions as an immune checkpoint inhibitor (PMID: 29914571). ENTPD1 (CD39) high expression in the tumor microenvironment has been implicated as a prognostic biomarker in a variety of tumor types, including gastric, hepatocellular, and chronic lymphocytic leukemia (PMID: 29914571, PMID: 28258700).
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