Gene Detail

Gene Symbol IKBKE
Synonyms IKK-E | IKK-i | IKKE | IKKI
Gene Description IKBKE, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon, is an I-kappaB family member that regulates activation of NF-kappaB signaling in response to inflammation and infection (PMID: 15102433, PMID: 26025939). IKBKE is over expressed in several tumor types, and is amplified in triple-negative breast cancer (PMID: 26025939, PMID: 25365225).
Entrez Id 9641
Chromosome 1
Map Location 1q32.1
Canonical Transcript NM_014002

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