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Gene Symbol SH3PXD2A
Synonyms FISH | SH3MD1 | TKS5
Gene Description SH3PXD2A, SH3 and PX domains 2A, encodes for an adaptor protein that is a substrate of Src and plays a role in forming podosomes and invadosomes, which influence the extracellular matrix (PMID: 25259869). The fusion, SH3PXD2A-HTRA1, has been identified in schwannoma (PMID: 27723760).
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