Gene Detail

Gene Symbol DOCK4
Gene Description DOCK4, dedicator of cytokinesis protein 4, activates Rap GTPase to regulate formation of intercellular adherens junctions and cell migration (PMID: 12628187). Overexpression of Dock4 may indicate risk of bone metastasis in breast cancer (PMID: 30426503) and a DOCK4-BRAF fusion has been identified in non-small cell lung cancer (PMID: 29883838).
Entrez Id 9732
Chromosome 7
Map Location 7q31.1
Canonical Transcript NM_014705

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