Gene Detail

Gene Symbol MELK
Synonyms HPK38
Gene Description MELK, maternal embryonic leucine zipper kinase, is a serine/threonine-protein kinase that plays a role in regulation of the cell cycle, cell proliferation, and apoptosis (PMID: 30334367). Overexpression of Melk has been observed in a variety of tumor types, including cervical cancer (PMID: 30334367), hepatocellular carcinoma (PMID: 29151817), breast cancer (PMID: 27225691), melanoma (PMID: 29212029), and leukemia (PMID: 25365263).
Entrez Id 9833
Chromosome 9
Map Location 9p13.2
Canonical Transcript NM_014791


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