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|Gene Variant Descriptions||MPL R390C lies within the fibronectin type-III domain 2 of the Mpl protein (UniProt.org). R390C has been identified in sequencing studies (PMID: 24755471, PMID: 31555481), but has not been biochemically characterized and therefore, its effect on Mpl protein function is unknown (PubMed, Mar 2020).|
|Associated Drug Resistance|
|Transcript||gDNA||cDNA||Protein||Source Database||Genome Build|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Molecular Profile||Protein Effect||Treatment Approaches|