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Gene PALB2
Variant D803N
Impact List missense
Protein Effect unknown
Gene Variant Descriptions PALB2 D803N lies within a region of the Palb2 protein required for POLH interaction and POLH DNA synthesis stimulation (UniProt.org). D803N has not been characterized in the scientific literature and therefore, its effect on Palb2 protein function is unknown (PubMed, Oct 2023).
Associated Drug Resistance
Category Variants Paths

PALB2 mutant PALB2 D803N

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Transcript NM_024675.4
gDNA chr16:g.23629747C>T
cDNA c.2407G>A
Protein p.D803N
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017023672 chr16:g.23629747C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
NM_001407309.1 chr16:g.23603491C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
NM_001407297.1 chr16:g.23629747C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
NM_001407301.1 chr16:g.23629747C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
NM_001407308.1 chr16:g.23603491C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
XM_011545947.2 chr16:g.23629753C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
XM_017023671.1 chr16:g.23629753C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
NM_001407298.1 chr16:g.23629747C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
NM_024675.3 chr16:g.23629747C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
XM_017023672.2 chr16:g.23629747C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
XM_017023671 chr16:g.23629753C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
NM_001407299.1 chr16:g.23629747C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
NM_001407300.1 chr16:g.23629747C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
NM_024675 chr16:g.23629747C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
XM_011545946.2 chr16:g.23629753C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
XM_017023673 chr16:g.23629747C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
XM_011545947 chr16:g.23629753C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
XM_017023673.2 chr16:g.23629747C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
NM_024675.4 chr16:g.23629747C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
NM_001407302.1 chr16:g.23629747C>T c.2407G>A p.D803N RefSeq GRCh38/hg38
XM_011545946 chr16:g.23629753C>T c.2407G>A p.D803N RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References