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Gene | STK11 |
Variant | D237Y |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | STK11 D237Y lies within the protein kinase domain of the Stk11 protein (UniProt.org). D237Y has been identified in the scientific literature (PMID: 32642098, PMID: 35831213), but has not been biochemically characterized and therefore, its effect on Stk11 protein function is unknown (PubMed, Oct 2023). |
Associated Drug Resistance | |
Category Variants Paths |
STK11 mutant STK11 D237Y |
Transcript | NM_000455.5 |
gDNA | chr19:g.1220692G>T |
cDNA | c.709G>T |
Protein | p.D237Y |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001407255.1 | chr19:g.1220692G>T | c.709G>T | p.D237Y | RefSeq | GRCh38/hg38 |
NM_000455.4 | chr19:g.1220692G>T | c.709G>T | p.D237Y | RefSeq | GRCh38/hg38 |
NM_000455.5 | chr19:g.1220692G>T | c.709G>T | p.D237Y | RefSeq | GRCh38/hg38 |
XM_005259618.3 | chr19:g.1220692G>T | c.709G>T | p.D237Y | RefSeq | GRCh38/hg38 |
NM_000455 | chr19:g.1220692G>T | c.709G>T | p.D237Y | RefSeq | GRCh38/hg38 |
XM_005259617 | chr19:g.1220692G>T | c.709G>T | p.D237Y | RefSeq | GRCh38/hg38 |
XM_005259617.3 | chr19:g.1220692G>T | c.709G>T | p.D237Y | RefSeq | GRCh38/hg38 |
XM_005259618 | chr19:g.1220692G>T | c.709G>T | p.D237Y | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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