Gene Variant Detail

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Gene CDK12
Variant E1327D
Impact List missense
Protein Effect unknown
Gene Variant Descriptions CDK12 E1327D does not lie within any known functional domains of the Cdk12 protein (UniProt.org). E1327D has not been characterized in the scientific literature and therefore, its effect on Cdk12 protein function is unknown (PubMed, Oct 2023).
Associated Drug Resistance
Category Variants Paths

CDK12 mutant CDK12 E1327D

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Transcript NM_016507.4
gDNA chr17:g.39530824G>C
cDNA c.3981G>C
Protein p.E1327D
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017024749.1 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_047436259.1 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524899 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_047436256.1 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524903 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524901.2 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_017024744 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524897.3 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
NM_016507.4 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524900 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524893.2 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_017024745 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524899.2 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_017024747 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524906 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524896.2 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524894 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524895.3 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_017024746 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524901 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_017024747.1 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524898.2 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524896 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524897.2 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524902.2 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524895.2 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524906.3 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524897 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
NM_016507.3 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_017024748 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524906.2 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
NM_016507 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_047436261.1 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524903.2 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524894.3 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_047436260.1 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_024450801.1 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524900.2 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524893.3 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524898.3 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524894.2 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524902 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524905.2 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_047436258.1 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_017024748.1 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524895 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524898 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_047436257.1 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_047436255.1 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_017024749 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524905 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38
XM_011524893 chr17:g.39530824G>C c.3981G>C p.E1327D RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References