Gene Variant Detail

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Gene AXL
Variant R308C
Impact List missense
Protein Effect unknown
Gene Variant Descriptions AXL R308C lies within fibronectin type-III domain 1 of the Axl protein (UniProt.org). R308C has not been characterized in the scientific literature and therefore, its effect on Axl protein function is unknown (PubMed, Aug 2022).
Associated Drug Resistance

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Transcript NM_021913.4
gDNA chr19:g.41238082C>T
cDNA c.922C>T
Protein p.R308C
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_021913.4 chr19:g.41238082C>T c.922C>T p.R308C RefSeq GRCh38/hg38
NM_021913 chr19:g.41238082C>T c.922C>T p.R308C RefSeq GRCh38/hg38
NM_001278599 chr19:g.41252365_41252367delAGGinsTGT c.922_924delAGGinsTGT p.R308C RefSeq GRCh38/hg38
NM_001278599.1 chr19:g.41252365_41252367delAGGinsTGT c.922_924delAGGinsTGT p.R308C RefSeq GRCh38/hg38
NM_001699.5 chr19:g.41238082C>T c.922C>T p.R308C RefSeq GRCh38/hg38
NM_001699 chr19:g.41238082C>T c.922C>T p.R308C RefSeq GRCh38/hg38

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  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Molecular Profile Protein Effect Treatment Approaches
AXL R308C unknown