Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Gene Variant Descriptions||NOTCH1 A2256fs results in a change in the amino acid sequence of the Notch1 protein beginning at aa 2256 of 2555, likely resulting in premature truncation of the functional protein (UniProt.org). A2256fs has been identified in the scientific literature (PMID: 25564152), but has not been biochemically characterized and therefore, its effect on Notch1 protein function is unknown.|
|Associated Drug Resistance|
|Transcript||gDNA||cDNA||Protein||Source Database||Genome Build|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Molecular Profile||Protein Effect||Treatment Approaches|