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|Gene Variant Descriptions||CALR K414E lies within the C-domain region of the Calr protein (UniProt.org). K414E has been identified in the scientific literature (PMID: 29218307), but has not been biochemically characterized and therefore, its effect on Calr protein function is unknown (PubMed, Feb 2020).|
|Associated Drug Resistance|
|Transcript||gDNA||cDNA||Protein||Source Database||Genome Build|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Molecular Profile||Protein Effect||Treatment Approaches|