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Gene | STK11 |
Variant | I248T |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | STK11 I248T lies within the protein kinase domain of the Stk11 protein (UniProt.org). I248T has not been characterized in the scientific literature and therefore, its effect on Stk11 protein function is unknown (PubMed, Oct 2023). |
Associated Drug Resistance | |
Category Variants Paths |
STK11 mutant STK11 I248T |
Transcript | NM_000455.5 |
gDNA | chr19:g.1221221T>C |
cDNA | c.743T>C |
Protein | p.I248T |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
XM_011528209 | chr19:g.1223029T>C | c.743T>C | p.I248T | RefSeq | GRCh38/hg38 |
XM_011528209.2 | chr19:g.1223029T>C | c.743T>C | p.I248T | RefSeq | GRCh38/hg38 |
XM_005259618.3 | chr19:g.1221221T>C | c.743T>C | p.I248T | RefSeq | GRCh38/hg38 |
NM_000455.5 | chr19:g.1221221T>C | c.743T>C | p.I248T | RefSeq | GRCh38/hg38 |
XM_005259618 | chr19:g.1221221T>C | c.743T>C | p.I248T | RefSeq | GRCh38/hg38 |
NM_000455.4 | chr19:g.1221221T>C | c.743T>C | p.I248T | RefSeq | GRCh38/hg38 |
NM_000455 | chr19:g.1221221T>C | c.743T>C | p.I248T | RefSeq | GRCh38/hg38 |
XM_005259617 | chr19:g.1221221T>C | c.743T>C | p.I248T | RefSeq | GRCh38/hg38 |
XM_005259617.3 | chr19:g.1221221T>C | c.743T>C | p.I248T | RefSeq | GRCh38/hg38 |
NM_001407255.1 | chr19:g.1221221T>C | c.743T>C | p.I248T | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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