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|Gene Variant Descriptions||CBL H94Y lies within the Cbl-PTB domain of the Cbl protein (UniProt.org). H94Y in combination with S80N results in ubiquitin activity similar to wild-type Cbl (PMID: 26676746), altered cell cycle, and increased cell viability and motility in cell culture (PMID: 20126411), however, has not been individually characterized and therefore, its effect on Cbl protein function is unknown.|
|Associated Drug Resistance|
|Transcript||gDNA||cDNA||Protein||Source Database||Genome Build|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Molecular Profile||Protein Effect||Treatment Approaches|