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|Variant||ETV6 - ABL2|
|Protein Effect||gain of function|
|Gene Variant Descriptions||ETV6-ABL2 (also known as TEL-ARG) results from the fusion of ETV6 and ABL2, demonstrating increased proliferation and increased phosphorylation of multiple cellular signaling proteins (PMID: 15005341, PMID: 25373509).|
|Associated Drug Resistance|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Molecular Profile||Protein Effect||Treatment Approaches|
|ETV6 - ABL2||gain of function|