Gene Variant Detail

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Gene MSH6
Variant R128H
Impact List missense
Protein Effect unknown
Gene Variant Descriptions MSH6 R128H lies within the PWWP domain of the Msh6 protein (UniProt.org). R128H has not been characterized and therefore, its effect on Msh6 protein function is unknown (PubMed, Oct 2019).
Associated Drug Resistance

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Transcript NM_000179
gDNA chr2:g.47791049G>A
cDNA c.383G>A
Protein p.R128H
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000179 chr2:g.47791049G>A c.383G>A p.R128H RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
MSH6 R128H unknown
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References