Gene Variant Detail

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Gene CDKN2A
Variant loss
Impact List unknown
Protein Effect loss of function
Gene Variant Descriptions CDKN2A loss indicates loss of the CDKN2A gene, mRNA and protein.
Associated Drug Resistance
Category Variants Paths

CDKN2A mutant CDKN2A inact mut CDKN2A loss

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No Variant Reference Transcript is Available.
No transcript is Available.

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
CDKN2A loss loss of function CDK Inhibitor (Pan) CDK4 Inhibitor CDK4/6 Inhibitor CDK6 Inhibitor
CDKN2A loss NRAS mut
CDKN2A loss NRAS Q61K
CDKN2A loss PIK3CA act mut
CDKN2A loss PIK3CA E542K PTEN loss
CDKN2A loss PIK3CA E545K PIK3CA amp
CDKN2A loss PIK3CA E542K PIK3CA amp
BRAF V600E/K CDKN2A loss RB1 pos
BRAF V600E CDKN2A loss NRAS Q61K
BRAF V600E CDKN2A loss NRAS G12V