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Gene MDM2
Variant V247A
Impact List missense
Protein Effect unknown
Gene Variant Descriptions MDM2 V247A lies within the acidic domain of the Mdm2 protein (PMID: 14707282). V247A has not been characterized in the scientific literature and therefore, its effect on Mdm2 protein function is unknown (PubMed, Jan 2024).
Associated Drug Resistance
Category Variants Paths

MDM2 mutant MDM2 V247A

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Transcript NM_001367990.1
gDNA chr12:g.68835902T>C
cDNA c.740T>C
Protein p.V247A
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_005268872 chr12:g.68835902T>C c.740T>C p.V247A RefSeq GRCh38/hg38
XM_005268872.5 chr12:g.68835902T>C c.740T>C p.V247A RefSeq GRCh38/hg38
NM_001367990.1 chr12:g.68835902T>C c.740T>C p.V247A RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References