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|Gene Variant Descriptions||SF3B1 D894G does not lie within any known functional domains of the Sf3b1 protein (UniProt.org). D894G did not alter cell proliferation as compared to wild-type Sf3b1 protein in cultured yeast cells (PMID: 32320410), but has not been fully biochemically characterized and therefore, its effect on Sf3b1 protein function is unknown (PubMed, Aug 2020).|
|Associated Drug Resistance|
|Transcript||gDNA||cDNA||Protein||Source Database||Genome Build|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Molecular Profile||Protein Effect||Treatment Approaches|