Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : firstname.lastname@example.org
|Gene Variant Descriptions||SMC3 R381Q does not lie within any known functional domains of the Smc3 protein (UniProt.org). R381Q has been identified in sequencing studies (PMID: 24335498, PMID: 27288520, PMID: 31303423), but has not been biochemically characterized and therefore, its effect on Smc3 protein function is unknown (PubMed, Mar 2020).|
|Associated Drug Resistance|
|Transcript||gDNA||cDNA||Protein||Source Database||Genome Build|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Molecular Profile||Protein Effect||Treatment Approaches|