Gene Variant Detail

Gene CTNNB1
Variant I35del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions CTNNB1 I35del results in the deletion of one amino acid in the Ctnnb1 protein at amino acid 35 (UniProt.org). I35del has not been characterized in the scientific literature and therefore, its effect on Ctnnb1 protein function is unknown (PubMed, Feb 2019).
Associated Drug Resistance

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Transcript NM_001098210
gDNA chr3:g.41224615_41224617delATC
cDNA c.103_105delATC
Protein p.I35delI
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001904 chr3:g.41224615_41224617delATC c.103_105delATC p.I35delI RefSeq GRCh38/hg38
NM_001098209 chr3:g.41224615_41224617delATC c.103_105delATC p.I35delI RefSeq GRCh38/hg38
XM_006712985 chr3:g.41224615_41224617delATC c.103_105delATC p.I35delI RefSeq GRCh38/hg38
XM_005264886 chr3:g.41224615_41224617delATC c.103_105delATC p.I35delI RefSeq GRCh38/hg38
XM_006712984 chr3:g.41224636_41224638delACA c.103_105delACA p.T35delT RefSeq GRCh38/hg38
NM_001098210 chr3:g.41224615_41224617delATC c.103_105delATC p.I35delI RefSeq GRCh38/hg38
XM_017005738 chr3:g.41224615_41224617delATC c.103_105delATC p.I35delI RefSeq GRCh38/hg38
XM_006712983 chr3:g.41224636_41224638delACA c.103_105delACA p.T35delT RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Protein Effect Treatment Approaches
CTNNB1 I35del unknown
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References