Gene Variant Detail

Gene CTNNB1
Variant V22_A97del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions CTNNB1 V22_A97del results in the deletion of 76 amino acids of the Ctnnb1 protein from amino acids 22 to 97 (UniProt.org). V22_A97del has been identified in sequencing studies (PMID: 24413733), but has not been biochemically characterized and therefore, its effect on Ctnnb1 protein function is unknown (PubMed, Feb 2019).
Associated Drug Resistance

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Transcript NM_001098210
gDNA chr3:g.41224576_41225003del428
cDNA c.64_291del428
Protein p.V22_A97del76
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001098210 chr3:g.41224576_41225003del428 c.64_291del428 p.V22_A97del76 RefSeq GRCh38/hg38
NM_001098209 chr3:g.41224576_41225003del428 c.64_291del428 p.V22_A97del76 RefSeq GRCh38/hg38
NM_001904 chr3:g.41224576_41225003del428 c.64_291del428 p.V22_A97del76 RefSeq GRCh38/hg38
XM_005264886 chr3:g.41224576_41225003del428 c.64_291del428 p.V22_A97del76 RefSeq GRCh38/hg38
XM_017005738 chr3:g.41224576_41225003del428 c.64_291del428 p.V22_A97del76 RefSeq GRCh38/hg38
XM_006712984 chr3:g.41224597_41225024del428 c.64_291del428 p.S22_D97del76 RefSeq GRCh38/hg38
XM_006712985 chr3:g.41224576_41225003del428 c.64_291del428 p.V22_A97del76 RefSeq GRCh38/hg38
XM_006712983 chr3:g.41224597_41225024del428 c.64_291del428 p.S22_D97del76 RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

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Molecular Profile Protein Effect Treatment Approaches
CTNNB1 V22_A97del unknown
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References