Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Variant||ETV6 - PRDM16|
|Protein Effect||gain of function - predicted|
|Gene Variant Descriptions||ETV6-PRDM16 results from the fusion of ETV6 and PRDM16 (PMID: 22050763). ETV6-PRDM16 has been identified in acute myeloid leukemia and myelodysplastic syndrome, but has not been biochemically characterized, however, has been demonstrated to result in over expression of PRDM16 (PMID: 22050763).|
|Associated Drug Resistance|
|Molecular Profile||Protein Effect||Treatment Approaches|
|ETV6 - PRDM16||gain of function - predicted|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|