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|Gene Variant Descriptions||NRAS Y64D does not lie within any known functional domains of the Nras protein (UniProt.org). Y64D does not promote tumor formation in animal models in a pooled screening assay, and induces a gene expression signature similar to wild-type Nras protein in culture in one study (PMID: 27147599), but has not been biochemically characterized, and therefore, its effect on Nras protein function is unknown.|
|Associated Drug Resistance|
|Transcript||gDNA||cDNA||Protein||Source Database||Genome Build|
|Molecular Profile||Protein Effect||Treatment Approaches|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|