Gene Variant Detail

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Gene APC
Variant A214V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC A214V lies within a coiled-coil domain of the Apc protein (UniProt.org). A214V has not been characterized in the scientific literature and therefore, its effect on Apc protein function is unknown (PubMed, Aug 2022).
Associated Drug Resistance
Category Variants Paths

APC mutant APC A214V

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Transcript NM_000038.5
gDNA chr5:g.112780899C>T
cDNA c.641C>T
Protein p.A214V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001354904.1 chr5:g.112792516C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354896.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354899.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354898.1 chr5:g.112792516C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_000038 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354903.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001127510 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
APC A214V unknown