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Gene APC
Variant C1410S
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC C1410S lies within the beta-catenin binding and downregulation region of the Apc protein (PMID: 14672538). C1410S has been identified in sequencing studies (PMID: 27147599), but has not been biochemically characterized and therefore, its effect on Apc protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC C1410S

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Transcript NM_000038.6
gDNA chr5:g.112839822T>A
cDNA c.4228T>A
Protein p.C1410S
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000038.6 chr5:g.112839822T>A c.4228T>A p.C1410S RefSeq GRCh38/hg38
NM_001127510 chr5:g.112839822T>A c.4228T>A p.C1410S RefSeq GRCh38/hg38
NM_000038 chr5:g.112839822T>A c.4228T>A p.C1410S RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112839822T>A c.4228T>A p.C1410S RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112839822T>A c.4228T>A p.C1410S RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112839822T>A c.4228T>A p.C1410S RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112839822T>A c.4228T>A p.C1410S RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112839822T>A c.4228T>A p.C1410S RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112839822T>A c.4228T>A p.C1410S RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries