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Gene FGFR2
Variant P256S
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR2 P256S lies within Ig-like C2-type domain 3 of the Fgfr2 protein (UniProt.org). P256S has been identified in sequencing studies (PMID: 25669975), but has not been biochemically characterized and therefore, its effect on Fgfr2 protein function is unknown (PubMed, Dec 2023).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 exon7 FGFR2 P256S

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Transcript NM_000141.5
gDNA chr10:g.121520152G>A
cDNA c.766C>T
Protein p.P256S
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_022970 chr10:g.121520152G>A c.766C>T p.P256S RefSeq GRCh38/hg38
NM_001144917.1 chr10:g.121520152G>A c.766C>T p.P256S RefSeq GRCh38/hg38
NM_000141.4 chr10:g.121520152G>A c.766C>T p.P256S RefSeq GRCh38/hg38
NM_001144917.2 chr10:g.121520152G>A c.766C>T p.P256S RefSeq GRCh38/hg38
NM_000141.5 chr10:g.121520152G>A c.766C>T p.P256S RefSeq GRCh38/hg38
NM_022970.3 chr10:g.121520152G>A c.766C>T p.P256S RefSeq GRCh38/hg38
NM_001320658 chr10:g.121520152G>A c.766C>T p.P256S RefSeq GRCh38/hg38
NM_001320658.2 chr10:g.121520152G>A c.766C>T p.P256S RefSeq GRCh38/hg38
NM_000141 chr10:g.121520152G>A c.766C>T p.P256S RefSeq GRCh38/hg38
NM_001320658.1 chr10:g.121520152G>A c.766C>T p.P256S RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121520152G>A c.766C>T p.P256S RefSeq GRCh38/hg38
NM_001144917 chr10:g.121520152G>A c.766C>T p.P256S RefSeq GRCh38/hg38
NM_001144913 chr10:g.121520152G>A c.766C>T p.P256S RefSeq GRCh38/hg38
NM_022970.4 chr10:g.121520152G>A c.766C>T p.P256S RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121520152G>A c.766C>T p.P256S RefSeq GRCh38/hg38

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References