Gene Variant Detail

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Gene FGFR3
Variant E216K
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR3 E216K lies within Ig-like C2-type domain 2 of the Fgfr3 protein (UniProt.org). E216K has not been characterized and therefore, its effect on Fgfr3 protein function is unknown (PubMed, Mar 2023).
Associated Drug Resistance
Category Variants Paths

FGFR3 mutant FGFR3 E216K

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Transcript NM_000142.4
gDNA chr4:g.1801650G>A
cDNA c.646G>A
Protein p.E216K
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011513422.1 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
XM_006713873 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
NM_001163213 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
NM_000142 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
XM_006713868.1 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
XM_006713871.1 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
NM_022965 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
NM_001163213.1 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
XM_011513420 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
XM_006713873.1 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
NM_000142.4 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
XM_006713872 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
NM_022965.3 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
XM_006713869.1 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
XM_011513420.1 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
NM_001354810.1 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
XM_006713869 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
XM_011513422 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
XM_006713868 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
NM_001354809.1 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
XM_006713870 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
XM_006713871 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38
XM_006713870.1 chr4:g.1801650G>A c.646G>A p.E216K RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References