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Gene ABL1
Variant S972L
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ABL1 S972L lies in the F-actin-binding region of the Abl1 protein (UniProt.org). S972L has been identified in sequencing studies (PMID: PMID: 25082755) but has not been biochemically characterized and therefore, its effect on Abl1 protein function is unknown (PubMed, Oct 2023).
Associated Drug Resistance
Category Variants Paths

ABL1 mutant ABL1 S972L

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Transcript NM_005157.6
gDNA chr9:g.130885205C>T
cDNA c.2915C>T
Protein p.S972L
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_005157.6 chr9:g.130885205C>T c.2915C>T p.S972L RefSeq GRCh38/hg38
NM_005157 chr9:g.130885205C>T c.2915C>T p.S972L RefSeq GRCh38/hg38
NM_005157.5 chr9:g.130885205C>T c.2915C>T p.S972L RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References