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Gene APC
Variant A2690T
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC A2690T does not lie within any known functional domains of the Apc protein (UniProt.org). A2690T has been identified in sequencing studies (PMID: 24082139), but has not been biochemically characterized and therefore, its effect on Apc protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC A2690T

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Transcript NM_000038.6
gDNA chr5:g.112843662G>A
cDNA c.8068G>A
Protein p.A2690T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000038 chr5:g.112843662G>A c.8068G>A p.A2690T RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112843662G>A c.8068G>A p.A2690T RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112843662G>A c.8068G>A p.A2690T RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112843662G>A c.8068G>A p.A2690T RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112843662G>A c.8068G>A p.A2690T RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112843662G>A c.8068G>A p.A2690T RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112843662G>A c.8068G>A p.A2690T RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112843662G>A c.8068G>A p.A2690T RefSeq GRCh38/hg38
NM_001127510 chr5:g.112843662G>A c.8068G>A p.A2690T RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
APC A2690T unknown