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Gene KIT
Variant exon 11 del
Impact List deletion
Protein Effect gain of function
Gene Variant Descriptions KIT exon 11 deletions are in-frame deletions within the juxtamembrane domain of the Kit protein (PMID: 26349547). KIT exon 11 deletions are associated with constitutive activation of Kit (PMID: 9438854, PMID: 15365079).
Associated Drug Resistance
Category Variants Paths

KIT mutant KIT act mut KIT exon 11 del

KIT mutant KIT exon11 KIT exon 11 del

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No Variant Reference Transcript is Available.
No transcript is Available.

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
KIT exon 11 del gain of function KIT Inhibitor
KIT exon 11 del KIT T670I
KIT exon 11 del KIT D816E
KIT exon 11 del KIT V654A
KIT exon 11 del KIT D816G
KIT exon 11 del KIT D816H
KIT exon 11 del KIT D820A
KIT exon 11 del KIT D820G
KIT exon 11 del KIT N822K
KIT exon 11 del KIT Y823D
KIT exon 11 del KIT A829P
KIT exon 11 del KIT exon13