Gene Variant Detail

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Gene CDH1
Variant D805*
Impact List nonsense
Protein Effect loss of function - predicted
Gene Variant Descriptions CDH1 D805* results in a premature truncation of the Cdh1 protein at amino acid 805 of 882 (UniProt.org). Due to the loss of the catenin-binding region (UniProt.org), D805* is predicted to lead to a loss of Cdh1 protein.
Associated Drug Resistance

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Transcript NM_004360
gDNA chr16:g.68829771_68829773delGATinsTAA
cDNA c.2413_2415delGATinsTAA
Protein p.D805*
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004360 chr16:g.68829771_68829773delGATinsTAA c.2413_2415delGATinsTAA p.D805* RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
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Molecular Profile Protein Effect Treatment Approaches
CDH1 D805* loss of function - predicted
Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References