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Gene FGFR3
Variant R805Q
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions FGFR3 R805Q does not lie within any known functional domains of the Fgfr3 protein (UniProt.org). R805Q has not been biochemically characterized, but results in similar cell proliferation and viability levels as wild-type Fgfr3 (PMID: 29533785) and therefore, is predicted to have no effect on Fgfr3 protein function.
Associated Drug Resistance
Category Variants Paths

FGFR3 mutant FGFR3 R805Q

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Transcript NM_000142.4
gDNA chr4:g.1807255G>A
cDNA c.2414G>A
Protein p.R805Q
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000142 chr4:g.1807255G>A c.2414G>A p.R805Q RefSeq GRCh38/hg38
NM_000142.4 chr4:g.1807255G>A c.2414G>A p.R805Q RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References